| Day | Date | Opponent | Location | Outcome/Time |
| Fri | 08/25/2000 | Iowa State Tournament - Ohio University | Ames, Iowa | L, 0-1
|
| Sun | 08/27/2000 | Iowa State | Ames, Iowa | T, 0-0
Recap |
| Tue | 08/29/2000 | Jacksonville State* | Birmingham, Ala. | W, 2-0
Recap |
| Tue | 09/05/2000 | Virginia | Charlottesville, Va. | L, 1-0
Recap |
| Fri | 09/08/2000 | Marquette* (UAB NIKE CLASSIC) | Birmingham, Ala. | L, 1-0
|
| Sun | 09/10/2000 | UTEP (UAB NIKE CLASSIC) | Birmingham, Ala. | L, 2-1
Recap |
| Fri | 09/15/2000 | South Florida* | Tampa, Fla. | T, 2-2
Recap |
| Sun | 09/17/2000 | Charlotte | Charlotte, N.C. | L, 3-0
Recap |
| Fri | 09/22/2000 | Auburn | Birmingham, Ala. | L, 2-0
|
| Sun | 09/24/2000 | DePaul* | Birmingham, Ala. | L, 3-1
Recap |
| Fri | 09/29/2000 | Southern Mississippi* | Hattiesburg, Miss. | L, 3-2
Recap |
| Sun | 10/01/2000 | Tulane* | New Orleans | L, 3-0
Recap |
| Fri | 10/06/2000 | Memphis* | Birmingham, Ala. | W, 4-0
Recap |
| Fri | 10/13/2000 | Cincinnati | Birmingham, Ala. | L, 2-1
Recap |
| Sun | 10/15/2000 | Louisville* | Birmingham, Ala. | W, 3-1
Recap |
| Tue | 10/17/2000 | Vanderbilt | Birmingham, Ala. | L, 4-1
Recap |
| Fri | 10/20/2000 | Houston* | Houston, TX. | L, 2-1
Recap |
| Sun | 10/22/2000 | St. Louis | St. Louis, Mo. | L, 3-1
Recap |
| Fri | 10/27/2000 | Mississippi | Oxford, Miss. | L, 3-0
Recap |
* Conference USA Match
^Doubleheader With UAB Men's team
All Times Local
Home games played at West Campus Field
(th Ave. So. & 11th St. So.)
